Plasma cell-free DNA (cf-DNA) has recently emerged as a new biomarker of age-associated systemic inflammation and cell death. . In this study we analyzed the associations between the distinct cf-DNA species (i.e. unmethylated cf-DNA, mitochondrial DNA, RNAse P gene-coding cf-DNA,…
Research news: Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study. Advanced age is typically accompanied with low-grade inflammation – a phenomenon that has also been demonstrated to predict longevity in several studies.…
Post Doctoral researcher Elina Sillanpää was awarded in Young scientist competition organized by the Finnish Society of Sport Sciences in Jyväskylä June 12, 2013. Her presentation and research abstract was based on article ”Muscle power is associated with ventilatory function…
The title of the thesis is Socioeconomic differences in health of the oldest old. The award was given at the national congress of Gerontology June 7, 2013. Gerontology Research Center;PO Box 35, FI-40014 University of JyväskyläStreet Address: Rautpohjankatu 8Gerontology Research…
Research news: Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: A transcriptomic analysis Ageing is associated with declining function of the immune system. Cytomegalovirus (CMV) has been associated with these changes. CMV is a herpes…
The Academy of Finland's Research Council for Health has awarded research funding for PhD Mikaela von Bonsdorff and PhD Elina Sillanpää At its meeting on 6 June 2012, the Academy of Finland’s Research Council for Health decided on funding for…
If successful aging is defined by using conventional criteria that emphasize absence of disease and disability, it is rare among nonagenarians. Doctoral student Lily Nosraty investigated the prevalence of successful aging and its association with sociodemographic factors in a representative…
The latest postal survey conducted by the Vitality 90+ study showed that health and functional ability vary greatly in the nonagenarian age group. Over a third of the 90+-year-olds lives independently and does not need help even with the more…
Mobility is important for community independence. With increasing age underlying pathologies genetic vulnerabilities, physiological and sensory impairments and environmental barriers increase the risk for mobility decline. The literature review broadens the understanding of how mobility decline is paramount to finding…
Knee osteoarthritis patients aged ≥ 75 years, who were scheduled for knee replacement, were compared with those who or had undergone knee replacement one year earlier, or two years earlier, respectively. Those who had experienced knee replacement, had better mobility,…
A research group from the Gerontology Research Center, based at the University of Jyväskylä’s Department of Health Sciences, received a three-year research grant from the Academy of Finland in the call "Active and Healthy Ageing Across the Life Course" by…
Sheltered housing with 24-hour assistance has replaced long-term care in residential homes. Residential homes and specially sheltered housing units are not able to care for old people until the end of life, but people are moved to other place of…